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Test Name: Potassium (K), Blood

Specimen Type: Serum/Plasma

Specimen Required: 3-5 Cc Yellow Top Gel Vial, Green top

Lithium Heparin Vial

Day Performed: Daily

Reporting Time: 8 Hours  STAT Reporting Time: 120 MINUTES

Methodology: Beckman Coulter AU480

CLINICAL SIGNIFICANCE:

High levels of potassium (hyperkalemia) may be due to:

  • Addison disease (rare)
  • Blood transfusion
  • Certain medicines, including angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), the potassium-sparing diuretics spironolactone, amiloride and triamterene, and beta adrenergic blockers
  • Crushed tissue injury
  • Hyperkalemic periodic paralysis
  • Hypoaldosteronism (very rare)
  • Kidney insufficiency or failure
  • Metabolic or respiratory acidosis
  • Red blood cell destruction
  • Too much potassium in the diet

Low levels of potassium (hypokalemia) may be due to:

  • Acute or chronic diarrhea
  • Cushing syndrome (rare)
  • Diuretics such as hydrochlorothiazide, furosemide, torsemide, and indapamide
  • Hyperaldosteronism
  • Hypokalemic periodic paralysis
  • Not enough potassium in the diet
  • Renal artery stenosis
  • Renal tubular acidosis (rare)
  • Vomiting

References:

  1. Mount DB. Disorders of potassium balance. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector’s The Kidney.11th ed. Philadelphia, PA: Elsevier; 2020: chap 17.
  2. Patney V, Whaley-Connell A. Hypokalemia and hyperkalemia. In: Lerma EV, Sparks MA, Topf JM, eds. Nephrology Secrets.4th ed. Philadelphia, PA: Elsevier; 2019: chap 74.
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