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Test Name: Phosphorous, Blood

Specimen Type: Serum

Specimen Required: 3-5 Cc Yellow Top Gel Vial

Day Performed: Daily

Reporting Time: 8 Hours  STAT Reporting Time: 120 MINUTES

Methodology: Beckman Coulter AU480

CLINICAL SIGNIFICANCE:

A higher than normal level (hyperphosphatemia) may be due to many different health conditions. Common causes include:

  • Diabetic ketoacidosis
  • Hypoparathyroidism
  • Kidney damage or failure
  • Liver disease
  • Too much vitamin D
  • Too much phosphate in your diet
  • Use of certain medicines such as laxatives that have phosphate in them

A lower than normal level (hypophosphatemia) may be due to:

  • Alcoholism
  • Hypercalcemia
  • Primary hyperparathyroidism 
  • Too little dietary intake of phosphate
  • Very poor nutrition
  • Too little vitamin D, resulting in bone problems such as rickets (childhood) or osteomalacia (adult)

References:

  1. Chonchol M, Smogorzewski MJ, Stubbs JR, Yu ASL. Disorders of calcium, magnesium, and phosphate balance. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector’s The Kidney. 11th ed. Philadelphia, PA: Elsevier; 2020: chap 18.
  2. Klemm KM, Klein MJ. Zhang Y. Biochemical markers of bone metabolism. In: McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022: chap 16.
  3. Kliegman RM, Stanton BF, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM. Electrolyte and acid-base disorders. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatric 21st ed. Philadelphia, PA: Elsevier; 2020: chap 68.
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