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Test Name: Ferritin, Blood

Specimen Type: Serum

Specimen Required: 3-5 Cc Yellow Top Gel Vial

Day Performed: Daily

Reporting Time: 8-24 Hours   

Methodology: Beckman Coulter Access II/ Snibe Maglumi 4000

CLINICAL SIGNIFICANCE:

A higher-than-normal ferritin level may be due to:

  • Liver disease due to alcohol abuse
  • An autoimmune disorder, such as rheumatoid arthritis
  • Frequent transfusion of red blood cells
  • Too much iron in the body (hemochromatosis)

A lower-than-normal level of ferritin occurs if anemia is caused by low iron levels in the body. This type of anemia may be due to:

  • A diet too low in iron
  • Heavy bleeding from an injury
  • Heavy menstrual bleeding
  • Poor absorption of iron from food, medicines, or vitamins
  • Bleeding in the esophagus, stomach, or intestines

References:

  1. Brittenham GM. Disorders of iron homeostasis: iron deficiency and overload. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018: chap 36.
  2. Camaschella C. Microcytic and hypochromic anemias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020: chap 150.
  3. Dominiczak MH. Vitamins and minerals. In: Baynes JW, Dominiczak MH, eds. Medical Biochemistry. 5th ed. Elsevier; 2019: chap 7.
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